ACRODERMATITIS ENTEROPATHIC (Brandt syndrome, Danbolt-Kloss syndrome). The disease of infants coincides with the beginning of complementary foods,
etiology and pathogenesis. At the heart of the disease is a deficiency of zinc in the body due to its insufficient intake with food or with impaired absorption in the intestine. Zinc deficiency reduces the activity of many enzymes and underlies metabolic disorders, especially carbohydrates and proteins.
The clinical picture. Vesicular, pustular, bullous dermatitis of the distal parts, limbs, around the natural openings of the body, often alopecia, loss of eyebrows and eyelashes, damage to the mucous membranes of yeast-like fungi, gastrointestinal upsets (diarrhea, steatorrhea, profuse with an unpleasant odor of excrement). In the future – malnutrition, secondary purulent infection, stunted growth.
The diagnosis is confirmed by the detection of low levels of zinc in the blood.
A differential diagnosis must be carried out with a syndrome of impaired intestinal absorption, dermatitis.
Treatment. Zinc sulfate up to 100-150 mg / day for
2-3 months, enzyme preparations.
The prognosis for early recognition and treatment is favorable.
Prevention – compliance with the rules of feeding in accordance with the age of the child.